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Review
. 2006 Feb 18;332(7538):401-6.
doi: 10.1136/bmj.332.7538.401.

Pregnancy and Congenital Heart Disease

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Free PMC article
Review

Pregnancy and Congenital Heart Disease

Anselm Uebing et al. BMJ. .
Free PMC article

Figures

Fig 1
Fig 1
Cardiovascular changes during pregnancy (adapted from Thorne with permission). Plasma volume and cardiac output increase steadily until the end of the second trimester, when cardiac output reaches a plateau at 30-50% above pre-pregnancy levels. Obstructive heart lesions (such as aortic or mitral valve stenosis), which limit cardiac output, are particularly compromised during pregnancy. The increase in blood volume may precipitate heart failure. Cyanosis often worsens during pregnancy as pregnancy related systemic vasodilation may lead to increased right to left shunting.
Fig 2
Fig 2
Proposed algorithm for anticoagulation therapy during pregnancy for women with congenital heart disease (modified from Elkayam20)

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