Abstract
New findings from neuroscience, genetics, and experimental psychology have emerged that provide alternative explanations of many negative symptoms. We review the continuing limitations in treatment and discuss possible sources of heterogeneity among negative symptoms. We also anticipate conceptual uncertainties that may arise with forthcoming treatment developments.
MeSH terms
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Antipsychotic Agents / pharmacology
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Antipsychotic Agents / therapeutic use*
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Drug Therapy / trends*
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Forecasting
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Frontal Lobe / physiopathology
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Humans
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Receptors, Dopamine D4 / drug effects
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Receptors, Dopamine D4 / genetics
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Schizophrenia / drug therapy*
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Schizophrenia / genetics
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Schizophrenia / physiopathology
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Schizophrenic Psychology*
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Surveys and Questionnaires
Substances
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Antipsychotic Agents
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Receptors, Dopamine D4