Abstract
5-aminosalicylates preparations are not superior to placebo for the maintenance of medically-induced remission in patients with Crohn's disease. We have to reconsider the potential risks associated with inhibition of lymphocyte trafficking since it can induce serious and potentially lethal infections. Infliximab has shown efficacy in active ulcerative colitis.
MeSH terms
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Adrenal Cortex Hormones / therapeutic use
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
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Antibodies, Monoclonal / therapeutic use
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Colitis, Ulcerative / drug therapy*
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Colitis, Ulcerative / immunology*
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Crohn Disease / drug therapy*
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Crohn Disease / immunology*
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Gastrointestinal Agents / therapeutic use
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Humans
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Infliximab
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Mesalamine / therapeutic use
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Risk Factors
Substances
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Adrenal Cortex Hormones
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Anti-Inflammatory Agents, Non-Steroidal
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Antibodies, Monoclonal
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Gastrointestinal Agents
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Mesalamine
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Infliximab