Neutralizing antibodies in survivors of Sin Nombre and Andes hantavirus infection

Emerg Infect Dis. 2006 Jan;12(1):166-8. doi: 10.3201/eid1201.050930.

Abstract

We evaluated titers of homotypic and heterotypic neutralizing antibodies (NAbs) to Andes and Sin Nombre hantaviruses in plasma samples from 20 patients from Chile and the United States. All but 1 patient had high titers of NAb. None of the plasma samples showed high titers against the heterologous virus.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antibodies, Viral / blood
  • Antibodies, Viral / immunology*
  • Chile / epidemiology
  • Hantavirus / immunology*
  • Hantavirus Pulmonary Syndrome / blood
  • Hantavirus Pulmonary Syndrome / epidemiology
  • Hantavirus Pulmonary Syndrome / immunology*
  • Hantavirus Pulmonary Syndrome / virology
  • Humans
  • Neutralization Tests
  • Sin Nombre virus / immunology*
  • Survivors*
  • United States / epidemiology

Substances

  • Antibodies, Viral