The toxic effects of cassava diets on humans were reviewed. Some newspapers in Nigeria have reported deaths associated with cassava meal consumption. The papers looked into the toxic factors in cassava, their causes, the resultant effects on humans, and the reasons why cassava diets became popular in Nigeria. Suggestions were made on how to process cassava to make it safe for human consumption. The reported deaths may have occurred due to improper processing. This may have left traces of hydrogen cyanide in the products and on consumption produced death.