Distribution of four capsular serotypes of Enterococcus faecalis among clinical isolates from different geographical origins and infection sites

Infection. 2006 Feb;34(1):22-5. doi: 10.1007/s15010-006-4100-5.


Background: Enterococci possess capsular polysaccharide antigens that are the targets of opsonic antibodies. These antibodies are potential candidates for development as immunotherapy.

Material and methods: The present study analyzes the distribution of four capsular serotypes within a collection of 157 isolates of Enterococcus faecalis from four countries with different sites of clinical infection.

Results: By using a capsular polysaccharide-specific ELISA, 42% of the isolates were grouped into one of four serogroups, and another 9% showed cross-reactivity between two serotype-specific sera. Heterogeneity of serotype distribution by both geographical origin and infection site was observed.

Conclusion: Half of the strain collection could be typed with four serotype-specific sera. No serotype from a given country or infection site clearly predominated.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Capsules / immunology*
  • Bacterial Typing Techniques
  • Enterococcus faecalis / classification*
  • Enterococcus faecalis / isolation & purification
  • Enzyme-Linked Immunosorbent Assay
  • Germany / epidemiology
  • Gram-Positive Bacterial Infections / epidemiology*
  • Gram-Positive Bacterial Infections / microbiology
  • Humans
  • Italy / epidemiology
  • Japan / epidemiology
  • Organ Specificity
  • Serotyping
  • United States / epidemiology