Noninvasive measures of oxidative stress status in humans

Free Radic Biol Med. 1991;10(3-4):177-84. doi: 10.1016/0891-5849(91)90073-c.


Although oxidative stress is thought to be involved in the pathophysiology of several diseases and aging, it is not routinely measured in clinical diagnosis. This is at least partly because accepted and standardized methods for measuring oxidative stress in humans are not yet established. One of the greatest needs in the field of free radical biology is the development of reliable methods for measuring oxidative stress status (OSS) in humans. A listing of some analytical approaches to measuring oxidative stress is provided as well as a listing of some noninvasive techniques that have been used in humans.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Aldehydes / metabolism
  • Electron Spin Resonance Spectroscopy
  • Humans
  • Hydrogen Peroxide / metabolism
  • Oxygen / metabolism*
  • Stress, Physiological
  • Superoxides / metabolism
  • Thiobarbiturates / blood


  • Aldehydes
  • Thiobarbiturates
  • Superoxides
  • Hydrogen Peroxide
  • thiobarbituric acid
  • Oxygen