Health-related quality of life in patients with trachomatous trichiasis or entropion

Ophthalmic Epidemiol. 2006 Feb;13(1):59-66. doi: 10.1080/09286580500473803.

Abstract

Purpose: To determine the health-related quality of life in patients with trachomatous trichiasis or entropion, before and after intervention.

Methods: A prospective, case-control, interventional study. Health-related quality of life was evaluated in 60 patients with trachomatous trichiasis or entropion, before and after intervention, and 60 age- and gender-matched controls without trichiasis or entropion, using the WHOQOL-Bref questionnaire. Thirty patients and controls had vision < 6/18, while 30 had vision = 6/18 in the better eye. The WHOQOL-Bref assesses four domains of quality of life: physical health (1), psychological health (2), social relationships (3), and environment (4). Domain scores of patients and controls and of patients before and after intervention were compared using Student's t-test. Patient characteristics were correlated with domain scores using Pearson's correlation.

Results: Quality of life was poorer than that of controls in domains 1 and 2 for patients with vision < 6/18 in the better eye (p < 0.001, p = 0.001, respectively), and in domains 1, 2 and 4 for patients with vision = 6/18 (p < 0.001, p < 0.001, p = 0.01, respectively). Scores improved after intervention in all domains except domain 3, even though vision did not improve.

Conclusions: Patients with trachomatous trichiasis or entropion suffer in the physical, psychological and environmental domains of health-related quality of life even when vision is normal. Timely intervention is essential not only to prevent corneal blindness but also to reduce the suffering caused by the non-visual symptoms. Future studies must identify barriers to therapeutic intervention, and attempts should be directed at overcoming them so as to reduce the non-blinding burden of trachoma.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Entropion / microbiology
  • Entropion / psychology*
  • Entropion / surgery
  • Eyelashes*
  • Female
  • Follow-Up Studies
  • Hair Diseases / microbiology
  • Hair Diseases / psychology*
  • Hair Diseases / surgery
  • Health Status*
  • Humans
  • India
  • Male
  • Middle Aged
  • Ophthalmologic Surgical Procedures
  • Prospective Studies
  • Quality of Life*
  • Trachoma / microbiology
  • Trachoma / psychology*
  • Trachoma / surgery
  • Treatment Outcome