A case of ovarian metastasis of gall bladder carcinoma simulating primary ovarian neoplasm: diagnostic pitfalls and review of literature

Int J Gynecol Cancer. 2006 Jan-Feb:16 Suppl 1:319-21. doi: 10.1111/j.1525-1438.2006.00335.x.


The ovary is a relatively frequent site of metastases from malignant neoplasia arising elsewhere in the body, the majority of these originating from the gastrointestinal tract. The best-known tumor of this type is signet ring cell adenocarcinoma (Krukenberg tumor) of gastric origin and large bowel. The gall bladder and bile ducts are extremely rare sources of these metastases. The casuistic describes a female patient, presented with pelvic mass and jaundice. While clinical and imaging results suggested a primary ovarian carcinoma with incidental cholelithiasis and choledocholithiasis, the final diagnosis was obtained on the basis of histopathologic findings of resected specimen.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma / diagnosis*
  • Adenocarcinoma / secondary
  • Adenocarcinoma / therapy
  • Antineoplastic Agents / therapeutic use
  • Cholecystectomy
  • Female
  • Fluorouracil / therapeutic use
  • Gallbladder Neoplasms / diagnosis*
  • Gallbladder Neoplasms / pathology
  • Gallbladder Neoplasms / therapy
  • Gynecologic Surgical Procedures
  • Humans
  • Leucovorin / therapeutic use
  • Middle Aged
  • Ovarian Neoplasms / diagnosis*
  • Ovarian Neoplasms / secondary
  • Ovarian Neoplasms / therapy


  • Antineoplastic Agents
  • Leucovorin
  • Fluorouracil