Skin metastasis in ovarian carcinoma

Int J Gynecol Cancer. Jan-Feb 2006;16 Suppl 1:414-8. doi: 10.1111/j.1525-1438.2006.00486.x.


We report a case of 69-year-old woman who presented with pleural metastasis of a serous papillary adenocarcinoma of the ovary. After chemotherapy and surgery, she had 2 years disease-free survival. After this period of time, she presented with a swollen leg, a cellulitis-like syndrome and erythematous nodules at lower abdominal wall and upper leg skin. The skin biopsy revealed metastasis of adenocarcinoma in the dermis. She died after 4 months of the diagnosis of the skin metastasis. In 20 years experience in our unit, it is the first time that we recognize a cutaneous metastasis in ovarian cancer.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma, Papillary / secondary*
  • Adenocarcinoma, Papillary / therapy
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
  • Carboplatin / administration & dosage
  • Disease-Free Survival
  • Fatal Outcome
  • Female
  • Gynecologic Surgical Procedures
  • Humans
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / therapy
  • Paclitaxel / administration & dosage
  • Pleural Neoplasms / secondary*
  • Pleural Neoplasms / therapy
  • Skin Neoplasms / secondary*
  • Skin Neoplasms / therapy


  • Carboplatin
  • Paclitaxel