The use of Alloderm in the closure of a giant omphalocele

J Pediatr Surg. 2006 Mar;41(3):e37-9. doi: 10.1016/j.jpedsurg.2005.12.067.


Giant omphaloceles are associated with a considerable loss of abdominal domain. Early primary repair of the fascia is either not possible or poorly tolerated by the infant. Current surgical options result in a ventral hernia requiring future surgery or involve the chronic use of prosthetic patches with or without tissue expanders. This case presentation describes an alternative surgical approach that results in early fascial closure using an interposition graft of Alloderm.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Wall / pathology
  • Abdominal Wall / surgery
  • Collagen / therapeutic use*
  • Digestive System Surgical Procedures / methods
  • Female
  • Hernia, Umbilical / surgery*
  • Humans
  • Infant, Newborn
  • Skin, Artificial*
  • Treatment Outcome


  • Alloderm
  • Collagen