[Effect of self-foot reflexology massage on depression, stress responses and immune functions of middle aged women]

Taehan Kanho Hakhoe Chi. 2006 Feb;36(1):179-88. doi: 10.4040/jkan.2006.36.1.179.
[Article in Korean]


Purpose: This study was aimed to identify the effects of a self-foot reflexology massage on depression, stress responses and functions of the immune system of middle-aged women.

Method: This study was a one group pretest-posttest experimental design and the data was collected from August 1st, 2004 to May 31st, 2005. The subjects consisted of 46 middle-aged women (40 - 64 years) who were recruited from the Community Health Center in Busan city. Subjects were not treated for 4 weeks, subsequently they were trained in self foot reflexology massage for 2 weeks, and then they did their own daily for 6 weeks (2 days at the research center, 5 days at home). The outcome variables were measured 4 times, at baseline, pre training, after training, and after the intervention. The collected data was analyzed using repeated measure ANOVA by the SPSS/WIN program.

Result: There was a statistically significant difference in depression, perceived stress, systolic blood pressure, natural-killer cells and Ig G. However, there was not a statistically significant difference in diastolic blood pressure, pulse or serum cortisol.

Conclusion: These results suggest that a self-foot reflexology massage could be utilized as an effective nursing intervention to reduce depression and stress responses, and to strengthen immune systems in middle-aged women.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Depression / immunology
  • Depression / nursing*
  • Female
  • Foot*
  • Humans
  • Immunoglobulin G / blood*
  • Killer Cells, Natural
  • Leukocyte Count
  • Massage*
  • Middle Aged
  • Stress, Psychological / immunology
  • Stress, Psychological / nursing*


  • Immunoglobulin G