High-fiber diet reduces serum estrogen concentrations in premenopausal women

Am J Clin Nutr. 1991 Sep;54(3):520-5. doi: 10.1093/ajcn/54.3.520.


The effect of dietary fiber on serum estrogen concentrations was studied in 62 premenopausal women. Their estimated daily dietary fiber intake was increased from an average of approximately 15 g to 30 g/d by supplementation with wheat, oat, or corn bran. This was done without any significant decrease in dietary fat consumption. After 2 mo on the high-fiber diets, the wheat-bran-supplemented group showed significant reductions in serum estrone (P less than 0.002) and estradiol (P less than 0.02) but no change in serum progesterone or sex-hormone-binding globulin concentrations. The serum estrogens were unaffected by dietary-fiber supplementation with oat or corn brans.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Dietary Fats / pharmacology
  • Dietary Fiber / pharmacology*
  • Edible Grain
  • Estrogens / blood*
  • Estrone / blood
  • Female
  • Humans
  • Menopause*
  • Middle Aged
  • Osmolar Concentration
  • Sex Hormone-Binding Globulin / analysis
  • Triticum
  • Zea mays


  • Dietary Fats
  • Dietary Fiber
  • Estrogens
  • Sex Hormone-Binding Globulin
  • Estrone