Preferential methylation of Wnt inhibitory factor-1 in acute promyelocytic leukemia: an independent poor prognostic factor

Leukemia. 2006 May;20(5):907-9. doi: 10.1038/sj.leu.2404176.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptor Proteins, Signal Transducing
  • Azacitidine / pharmacology
  • Biomarkers, Tumor / genetics
  • Biomarkers, Tumor / metabolism*
  • Carrier Proteins / genetics
  • Carrier Proteins / metabolism*
  • Cell Line, Tumor
  • Cell Proliferation / drug effects
  • Humans
  • Leukemia, Promyelocytic, Acute / diagnosis
  • Leukemia, Promyelocytic, Acute / drug therapy
  • Leukemia, Promyelocytic, Acute / physiopathology*
  • Methylation
  • Multivariate Analysis
  • Prognosis
  • RNA, Messenger / drug effects
  • RNA, Messenger / metabolism
  • Recurrence
  • Remission Induction
  • Repressor Proteins / genetics
  • Repressor Proteins / metabolism*
  • Reverse Transcriptase Polymerase Chain Reaction / methods
  • Risk Factors
  • Sensitivity and Specificity
  • Survival Rate
  • Tretinoin / therapeutic use
  • Tumor Cells, Cultured

Substances

  • Adaptor Proteins, Signal Transducing
  • Biomarkers, Tumor
  • Carrier Proteins
  • RNA, Messenger
  • Repressor Proteins
  • WIF1 protein, human
  • Tretinoin
  • Azacitidine