NF-kappaB and the regulation of hematopoiesis

Cell Death Differ. 2006 May;13(5):785-97. doi: 10.1038/sj.cdd.4401888.

Abstract

This review will focus on the role of nuclear factor kappaB (NF-kappaB) signaling in hematopoietic differentiation. We will also discuss several hematopoietic pathologies associated with deregulation of NF-kappaB and their potential therapies.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cell Differentiation*
  • Dendritic Cells / metabolism
  • Dendritic Cells / physiology
  • Graft Rejection / metabolism
  • Hematologic Diseases / metabolism*
  • Hematopoiesis*
  • Humans
  • Myeloid Cells / metabolism
  • NF-kappa B / metabolism*
  • Signal Transduction
  • T-Lymphocytes / metabolism
  • T-Lymphocytes / physiology

Substances

  • NF-kappa B