Micro RNAs in animal development

Cell. 2006 Mar 10;124(5):877-81. doi: 10.1016/j.cell.2006.02.030.

Abstract

Micro RNAs (miRNAs) are approximately 22 nucleotide single-stranded noncoding RNA molecules that bind to target messenger RNAs (mRNAs) and silence their expression. This Essay explores the importance of miRNAs in animal development and their possible roles in disease and evolution.

MeSH terms

  • Animals
  • Biological Evolution
  • Disease
  • Embryo, Mammalian / physiology*
  • Gene Expression Regulation, Developmental*
  • Humans
  • MicroRNAs / metabolism*
  • RNA, Messenger / metabolism

Substances

  • MicroRNAs
  • RNA, Messenger