Mitosis-specific Kinesins in Arabidopsis

Trends Plant Sci. 2006 Apr;11(4):167-75. doi: 10.1016/j.tplants.2006.02.004. Epub 2006 Mar 10.

Abstract

Kinesins are a class of microtubule-associated proteins that possess a motor domain for binding to microtubules and, in general, allows movement along microtubules. In animal mitosis, they function in spindle formation, chromosome movement and in cytokinesis. In addition to the spindle, plants develop a preprophase band and a phragmoplast that might require multiple kinesins for construction and functioning. Indeed, several kinesins play a role in phragmoplast and cell plate dynamics. Surprisingly few kinesins have been associated with the spindle and the preprophase band. Analysis of expression datasets from synchronized cell cultures indicate that at least 23 kinesins are in some way implicated in mitosis-related processes. In this review, the function of kinesins in animal and plant mitoses are compared, and the divergence that originates from plant-specific aspects is highlighted.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Arabidopsis / cytology
  • Arabidopsis / genetics
  • Arabidopsis / metabolism*
  • Arabidopsis Proteins / genetics
  • Arabidopsis Proteins / metabolism
  • Arabidopsis Proteins / physiology*
  • Kinesin / genetics
  • Kinesin / metabolism
  • Kinesin / physiology*
  • Mitosis / physiology*
  • Multigene Family / physiology
  • Phosphorylation
  • Sequence Homology, Amino Acid
  • Up-Regulation

Substances

  • Arabidopsis Proteins
  • Kinesin