Staining the anterior capsule with indocyanine green or trypan blue for capsulorhexis in eyes with white cataract

Int Ophthalmol. 2004 Oct-Dec;25(5-6):273-6. doi: 10.1007/s10792-005-2228-4. Epub 2006 Mar 7.

Abstract

Aim: To assess the efficacy and safety of indocyanine green (ICG) 0.5% and trypan blue 0.1% for anterior capsule staining in cases of white cataract.

Methods: This prospective study comprised 55 eyes of 55 patients with white cataract that had phacoemulsification with foldable intraocular lens implantation. ICG in 30 eyes and trypan blue in 25 eyes were used under air to stain the anterior lens capsule. The staining patterns and the ease of creating a continuous curvilinear capsulorhexis (CCC) were assessed; the intraoperative and postoperative complications were noted. The mean follow-up was 17.68+/-1.65 months.

Result: Either ICG or trypan blue stained the anterior capsule uniformly. However, the staining provided by trypan blue was slightly superior. A CCC was successfully achieved in 25 eyes (100%) with trypan blue, and 29 eyes (96.7%) with ICG, respectively. There was no significant postoperative reaction in any eye.

Conclusion: The use of vital dyes such as ICG and trypan blue guarantees a complete CCC and makes it possible to deliver the benefits of phacoemulsification in the patients with white cataract.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anterior Eye Segment
  • Capsulorhexis / methods*
  • Cataract / diagnosis*
  • Coloring Agents*
  • Female
  • Humans
  • Indocyanine Green*
  • Intraoperative Complications
  • Lens Capsule, Crystalline / pathology
  • Lens Capsule, Crystalline / surgery
  • Lens Implantation, Intraocular
  • Male
  • Middle Aged
  • Postoperative Complications
  • Prospective Studies
  • Staining and Labeling / methods
  • Treatment Outcome
  • Trypan Blue*
  • Visual Acuity

Substances

  • Coloring Agents
  • Trypan Blue
  • Indocyanine Green