Clinical correlation of gallstone disease in a Chinese population in Taiwan: experience at Cheng Hsin General Hospital

World J Gastroenterol. 2006 Feb 28;12(8):1281-6. doi: 10.3748/wjg.v12.i8.1281.

Abstract

Aim: To explore the prevalence of gallstone disease (GSD) in Taiwan and condition-associated factors related to it.

Methods: We studied a total of 2386 healthy adults (1235 males and 1151 females) voluntarily admitted to Cheng Hsin General Hospital for a paid physical check-up between January 2002 and December 2002. Blood samples and ultrasound sonography results were collected.

Results: The overall prevalence of GSD among this study-population was 5.3%, including 1.7% (n=40) having a single stone, 2.3% (n=55) having multiple stones, and 1.3% (n=31) having cholecystectomy. The prevalence revealed a statistically significant increase with increasing age (P<0.0001). Females exhibited a greater prevalence of multiple stones than did males (3.0% vs 1.7%, P=0.04). Using multiple logistic regression analysis, the following appeared to be significantly related to the prevalence of GSD: older age (40-49 years vs < 40 years, OR=1.63 [95% CI: 0.76-3.48], 50-59 years vs < 40 years, OR=4.93 [95% CI: 2.43-9.99], 60-69 years vs < 40 years, OR=6.82 [95% CI: 3.19-14.60], > or = 70 years vs < 40 years, OR=10.65 [95% CI: 4.78-23.73]), higher BMI (> or = 27 kg/m2 vs < 24 kg/m2, adjusted OR=1.74 [95% CI: 1.04-2.88]), and higher FPG (> or = 126 mg/dL vs < 110 mg/dL, OR=1.71, 95%CI: 1.01-2.96).

Conclusion: Older age (> or = 50 years), obesity (BMI > or = 27 kg/m2), and type 2 diabetes (FPG > or = 126 mg/dL) are associated with the prevalence of GSD.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Asian Continental Ancestry Group*
  • Body Mass Index
  • Cholelithiasis / epidemiology*
  • Cholelithiasis / ethnology
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / epidemiology
  • Female
  • Gallstones / epidemiology*
  • Gallstones / ethnology
  • Hospitals, General / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Obesity / complications
  • Obesity / epidemiology
  • Prevalence
  • Regression Analysis
  • Risk Factors
  • Taiwan / epidemiology