The effects of dimethylsulphoxide and 5-aminolaevulinic acid on the activities of cytochrome P450-dependent mixed function oxidase and UDP-glucuronosyl transferase activities in human Hep G2 hepatoma cells

Biochem Pharmacol. 1991 Aug 22;42(6):1307-13. doi: 10.1016/0006-2952(91)90271-6.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carcinoma, Hepatocellular / enzymology
  • Culture Media
  • Cytochrome P-450 Enzyme System / drug effects*
  • Cytochrome P-450 Enzyme System / metabolism
  • Dimethyl Sulfoxide / pharmacology*
  • Drug Interactions
  • Glucuronosyltransferase / drug effects*
  • Glucuronosyltransferase / metabolism
  • Humans
  • Levulinic Acids / pharmacology*
  • Liver / drug effects*
  • Liver / enzymology
  • Liver Neoplasms / enzymology
  • Mixed Function Oxygenases / drug effects*
  • Mixed Function Oxygenases / metabolism
  • Tumor Cells, Cultured / drug effects*
  • Tumor Cells, Cultured / enzymology

Substances

  • Culture Media
  • Levulinic Acids
  • Cytochrome P-450 Enzyme System
  • Mixed Function Oxygenases
  • Glucuronosyltransferase
  • Dimethyl Sulfoxide