2-Diazoacetoacetic acid, an efficient and convenient reagent for the synthesis of alpha-diazo-beta-ketoesters

Michael E Meyer; Eric M Ferreira; Brian M Stoltz

doi:10.1039/b517719g

2-Diazoacetoacetic acid, an efficient and convenient reagent for the synthesis of alpha-diazo-beta-ketoesters

Chem Commun (Camb). 2006 Mar 28:(12):1316-8. doi: 10.1039/b517719g. Epub 2006 Feb 15.

Authors

Michael E Meyer¹, Eric M Ferreira, Brian M Stoltz

Affiliation

¹ Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, MC 164-30, Pasadena, CA 91125, USA.

PMID: 16538259
DOI: 10.1039/b517719g

Abstract

The formation of various alpha-diazo acetoacetic esters can be obtained in a single transformation with good to excellent yields using readily available 2-diazoacetoacetic acid.