Genetics of type 2 diabetes

Curr Diab Rep. 2006 Apr;6(2):147-54. doi: 10.1007/s11892-006-0026-7.


After several years of uncertain progress, the stage is now set for a transformation in understanding the genetic landscape of type 2 diabetes. Advances in genome informatics, genotyping technology, and statistical methodology, allied to availability of large-scale clinical material, are having a salutary effect on susceptibility gene discovery. The advent of genuinely genome-wide association scans and the prospects for combining genetics with high-throughput genomics are additional sources of optimism for the future.

Publication types

  • Review

MeSH terms

  • Diabetes Mellitus, Type 2 / genetics*
  • Genetic Linkage*
  • Genetic Research
  • Humans
  • PPAR gamma / genetics
  • Potassium Channels, Inwardly Rectifying / genetics
  • Proteins / genetics
  • Research Design


  • Kir6.2 channel
  • PPAR gamma
  • Potassium Channels, Inwardly Rectifying
  • Proteins