Mitochondrial protein import: convergent solutions for receptor structure

Curr Biol. 2006 Mar 21;16(6):R197-9. doi: 10.1016/j.cub.2006.02.024.

Abstract

Complex machinery has evolved to recognise and import nuclear-encoded proteins into mitochondria. Recent work now shows that the plant Tom20 mitochondrial protein import receptor has a similar tertiary structure to animal Tom20, although the proteins are evolutionarily distinct, representing an elegant example of convergent evolution.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Evolution, Molecular*
  • Fungal Proteins / chemistry
  • Fungal Proteins / physiology
  • Fungi / metabolism
  • Membrane Proteins / chemistry*
  • Membrane Proteins / physiology
  • Mitochondria / metabolism
  • Mitochondrial Membranes / metabolism*
  • Mitochondrial Proteins / chemistry*
  • Mitochondrial Proteins / metabolism*
  • Plant Proteins / chemistry
  • Plant Proteins / physiology
  • Plants / metabolism
  • Protein Structure, Tertiary
  • Protein Transport

Substances

  • Fungal Proteins
  • Membrane Proteins
  • Mitochondrial Proteins
  • Plant Proteins