DNA Topoisomerases: Single Gyrase Caught in the Act

Curr Biol. 2006 Mar 21;16(6):R204-6. doi: 10.1016/j.cub.2006.02.029.

Abstract

A recent study has analysed the action of bacterial DNA gyrase on a single substrate DNA molecule, discriminating the initial DNA wrapping and subsequent supercoiling steps in the reaction cycle.

MeSH terms

  • DNA / chemistry
  • DNA / metabolism*
  • DNA Gyrase / chemistry
  • DNA Gyrase / metabolism*
  • Models, Genetic
  • Protein Subunits / metabolism

Substances

  • Protein Subunits
  • DNA
  • DNA Gyrase