Use of lymphoscintigraphy with SPECT/CT for sentinel node localization in a case of vaginal melanoma

Clin Nucl Med. 2006 Apr;31(4):201-2. doi: 10.1097/01.rlu.0000204201.69676.31.


A 45-year-old woman with vaginal melanoma underwent Tc-99m sulfur colloid (filtered) lymphoscintigraphy with the acquisition of planar and SPECT/CT images for localization of a sentinel node before surgery. The study identified both inguinal and perirectal sentinel nodes, which proved beneficial in mapping potential anatomic spread of disease for staging and therapy planning. These results provide evidence for the use of routine SPECT/CT imaging for pelvic lymphoscintigraphic studies or as an adjunct tool for localizing sentinel nodes in cases that would not be demonstrated with planar imaging alone.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Humans
  • Lymphatic Metastasis / diagnostic imaging*
  • Melanoma / diagnostic imaging*
  • Middle Aged
  • Radiopharmaceuticals
  • Technetium Tc 99m Sulfur Colloid
  • Tomography, Emission-Computed, Single-Photon*
  • Tomography, X-Ray Computed*
  • Vaginal Neoplasms / diagnostic imaging*


  • Radiopharmaceuticals
  • Technetium Tc 99m Sulfur Colloid