Coexistence of Crohn's disease and inflammatory fibroid polyp of the small bowel. Report of a case and review of the literature

Ann Ital Chir. Jul-Aug 2005;76(4):395-9.


Background/aim: The Authors report a case of a woman aged 35, with concurrent appearance of Crohns disease and Inflammatory Fibroid Polyp of the terminal ileum.

Case report: The combination of the two disorders was clinically manifested as an obstructive ileus. On the operative table, a 4-cm polypoid mass causing intussusception of the bowel was obvious. The resected specimen of the ileum showed profound distention, several ulcerations and fissures. The histological examination confirmed the diagnosis of Crohn's disease coexisting with an Inflammatory Fibroid Polyp. Immunostaining of the lesion for actin showed focal positivity. However, staining for desmin, CD31, S100-protein, PGM-1 CD34, CD117, and bc1-2, was negative.

Conclusion: Coexistence of Inflammatory Fibroid Polyp with Crohn's disease causing obstructive ileus could be the first manifestation of the disease. The combination of the two disorders corroborates the reparative character of the lesion. Nevertheless, the exact etiopathogenetic relationship between the two entities remains obscure.

Publication types

  • Case Reports

MeSH terms

  • Abdomen, Acute / etiology
  • Adult
  • Crohn Disease / complications*
  • Crohn Disease / diagnosis
  • Crohn Disease / pathology
  • Emergencies
  • Female
  • Humans
  • Ileal Diseases / complications*
  • Ileal Diseases / diagnosis
  • Ileal Diseases / pathology
  • Ileal Diseases / surgery
  • Ileum / pathology
  • Immunohistochemistry
  • Intestinal Polyps / complications*
  • Intestinal Polyps / diagnosis
  • Intestinal Polyps / pathology
  • Intussusception / diagnosis
  • Intussusception / etiology
  • Intussusception / pathology
  • Intussusception / surgery
  • Laparotomy