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Multicenter Study
. 2006 Apr 22;332(7547):947-51.
doi: 10.1136/bmj.38790.468519.55. Epub 2006 Mar 22.

Mortality associated with delay in operation after hip fracture: observational study

Alex Bottle  1 , Paul Aylin
Affiliations
Multicenter Study

Mortality associated with delay in operation after hip fracture: observational study

Alex Bottle et al. BMJ. .

Abstract

Objective: To estimate the number of deaths and readmissions associated with delay in operation after femoral fracture.

Design: Analysis of inpatient hospital episode statistics.

Setting: NHS hospital trusts in England with at least 100 admissions for fractured neck of femur during the study period. Patients People aged > or = 65 admitted from home with fractured neck of femur and discharged between April 2001 and March 2004.

Main outcome measures: In hospital mortality and emergency readmission within 28 days.

Results: There were 129,522 admissions for fractured neck of femur in 151 trusts with 18,508 deaths in hospital (14.3%). Delay in operation was associated with an increased risk of death in hospital, which was reduced but persisted after adjustment for comorbidity. For all deaths in hospital, the odds ratio for more than one day's delay relative to one day or less was 1.27 (95% confidence interval 1.23 to 1.32) after adjustment for comorbidity. The proportion with more than two days' delay ranged from 1.1% to 62.4% between trusts. If death rates in patients with at most one day's delay had been repeated throughout all 151 trusts in this study, there would have been an average of 581 (478 to 683) fewer total deaths per year (9.4% of the total). There was little evidence of an association between delay and emergency readmission.

Conclusions: Delay in operation is associated with an increased risk of death but not readmission after a fractured neck of femur, even with adjustment for comorbidity, and there is wide variation between trusts.

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Figures

Fig 1
Fig 1
Odds ratios of death within hospital by operative delay relative to at most one day's delay, after adjustment for age, sex, deprivation, type of procedure (fixation and replacement only), and selected comorbidities
Fig 2
Fig 2
Mean annual difference between observed and expected deaths in hospital per 1000 admissions by trust associated with an operative delay of more than one day
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