Biomedicine. Lowering LDL--not only how low, but how long?

Science. 2006 Mar 24;311(5768):1721-3. doi: 10.1126/science.1125884.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anticholesteremic Agents / therapeutic use*
  • Black or African American / genetics
  • Cholesterol, LDL / blood*
  • Codon, Nonsense
  • Coronary Disease / epidemiology
  • Coronary Disease / genetics
  • Coronary Disease / prevention & control*
  • Diet, Fat-Restricted
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
  • Incidence
  • Lipoproteins, LDL / blood*
  • Mice
  • Mutation, Missense
  • Proprotein Convertase 9
  • Proprotein Convertases
  • Serine Endopeptidases / genetics*
  • Serine Endopeptidases / metabolism*
  • Time Factors
  • White People / genetics

Substances

  • Anticholesteremic Agents
  • Cholesterol, LDL
  • Codon, Nonsense
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Lipoproteins, LDL
  • PCSK9 protein, human
  • Pcsk9 protein, mouse
  • Proprotein Convertase 9
  • Proprotein Convertases
  • Serine Endopeptidases