Initial European clinical experience with pulsatile extracorporeal membrane oxygenation

J Heart Lung Transplant. 2006 Apr;25(4):400-3. doi: 10.1016/j.healun.2005.11.455. Epub 2006 Feb 28.

Abstract

Background: Extracorporeal membrane oxygenation (ECMO) for post-cardiotomy heart failure in neonates and infants still carries high mortality and morbidity rates. In this study we present the first European clinical experience with the Medos DeltaStream DP1, a new pulsatile flow pump, in neonates and infants.

Methods: The DP1 is an extracorporeal rotary blood pump. The pump features a diagonal flow impeller, and can be used for both continuous and pulsatile output. Special characteristics include its small priming volume of approximately 30 ml and a high pumping capacity. A temperature sensor and speed sensors are integrated into the pump. The pump has a delivery rate of up to 8 liters/min and a speed range of 100 to 10,000 rpm.

Results: Two patients being assisted with the pulsatile pump system were successfully weaned after 36 and 53 hours, respectively.

Conclusions: Based on our limited experience with 2 patients, we believe that pulsatile DP1 device is a reasonable alternative to current conventional non-pulsatile systems.

Publication types

  • Case Reports

MeSH terms

  • Cardiac Surgical Procedures
  • Europe
  • Extracorporeal Membrane Oxygenation / instrumentation
  • Extracorporeal Membrane Oxygenation / methods*
  • Female
  • Heart Defects, Congenital / surgery
  • Heart Failure / etiology
  • Heart Failure / surgery*
  • Humans
  • Infant
  • Infant, Newborn
  • Mitral Valve Insufficiency / complications
  • Mitral Valve Insufficiency / congenital
  • Mitral Valve Insufficiency / surgery
  • Postoperative Complications*
  • Pulsatile Flow / physiology*
  • Reoperation
  • Ventricular Dysfunction, Left / etiology