Impact of hypnosis during embryo transfer on the outcome of in vitro fertilization-embryo transfer: a case-control study

Fertil Steril. 2006 May;85(5):1404-8. doi: 10.1016/j.fertnstert.2005.10.035. Epub 2006 Mar 29.


Objective: To investigate whether hypnosis during ET contributes to successful IVF/ET outcome.

Design: Case-control clinical study.

Setting: Academic Fertility and IVF Unit, Soroka Medical Center, Beer-Sheva, Israel.

Patient(s): Infertile couples undergoing IVF.

Intervention(s): Ninety-eight IVF/ET cycles with hypnosis during the ET procedure were matched with 96 regular IVF/ET cycles.

Main outcome measures: Comparison of clinical pregnancy and implantation rates between the two groups.

Result(s): We obtained 52 clinical pregnancies out of 98 cycles (53.1%) with an implantation rate of 28% among hypnosis IVF/ET cycles, and 29 out of 96 (30.2%) clinical pregnancies and an implantation rate of 14.4% in the control cycles. Our overall IVF program pregnancy rate for the same period was 32.1%. Logistic regression analysis was performed emphasizing the positive contribution of hypnosis to the IVF/ET conception rates.

Conclusion(s): This study suggests that the use of hypnosis during ET may significantly improve the IVF/ET cycle outcome in terms of increased implantation and clinical pregnancy rates. Furthermore, it seems that the patients' attitude to the treatment was more favorable.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Case-Control Studies
  • Combined Modality Therapy / statistics & numerical data
  • Embryo Transfer / statistics & numerical data*
  • Female
  • Fertilization in Vitro / statistics & numerical data*
  • Humans
  • Hypnosis / statistics & numerical data*
  • Incidence
  • Infertility / epidemiology*
  • Infertility / therapy*
  • Israel / epidemiology
  • Pregnancy / statistics & numerical data
  • Pregnancy Outcome / epidemiology*
  • Pregnancy Rate*
  • Recombinant Proteins / administration & dosage
  • Treatment Outcome


  • Recombinant Proteins