Variability in the region downstream of the blaCMY-2 beta-lactamase gene in Escherichia coli and Salmonella enterica plasmids

Min-Su Kang; Thomas E Besser; Douglas R Call

doi:10.1128/AAC.50.4.1590-1593.2006

Variability in the region downstream of the blaCMY-2 beta-lactamase gene in Escherichia coli and Salmonella enterica plasmids

Antimicrob Agents Chemother. 2006 Apr;50(4):1590-3. doi: 10.1128/AAC.50.4.1590-1593.2006.

Authors

Min-Su Kang¹, Thomas E Besser, Douglas R Call

Affiliation

¹ Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, 402 Bustad Hall, Pullman, WA 99164-7040, USA.

Abstract

We used sequencing and PCR mapping to investigate the regions flanking the blaCMY-2 beta-lactamase gene carried by plasmids from Escherichia coli and Salmonella enterica. Results revealed genetic heterogeneity in the region downstream from blaCMY-2 and identified a putative transposable element bearing blaCMY-2.

MeSH terms

Base Sequence
DNA Transposable Elements
Escherichia coli / enzymology
Escherichia coli / genetics*
Molecular Sequence Data
Plasmids*
Salmonella enterica / enzymology
Salmonella enterica / genetics*
beta-Lactamases / genetics*

Substances

DNA Transposable Elements
beta-lactamase CMY-2
beta-Lactamases

Associated data

GENBANK/DQ164214
GENBANK/DQ249311

Grants and funding

N01AI30055/AI/NIAID NIH HHS/United States