Recurrent lymphocytic hypophysitis in a woman 27 years after subtotal adrenalectomy for hypercortisolism possibly of autoimmune origin

J Assoc Physicians India. 2005 Dec;53:1066-9.


Lymphocytic hypophysitis commonly occurs in females in peripartum period but several unusual presentations have been reported. Here we report a rare case of recurrent lymphocytic hypophysitis in a woman who had subtotal adrenalectomy for hypercortisolism 27 years back. Polyglandular autoimmune endocrinopathy with an uncommon combination of Cushing's syndrome and recurrent hypophysitis is a strong possibility in this case. Treatment with steroids has been found to have beneficial effect.

Publication types

  • Case Reports

MeSH terms

  • Adrenalectomy*
  • Cushing Syndrome / complications
  • Cushing Syndrome / surgery*
  • Female
  • Humans
  • Inflammation / diagnosis
  • Inflammation / etiology
  • Inflammation / therapy
  • Leukocyte Disorders / diagnosis*
  • Leukocyte Disorders / etiology
  • Leukocyte Disorders / therapy
  • Middle Aged
  • Pituitary Diseases / diagnosis*
  • Pituitary Diseases / etiology
  • Pituitary Diseases / therapy
  • Recurrence