A superior P-H phosphonite: asymmetric allylic substitutions with fenchol-based palladium catalysts

Bernd Goldfuss; Thomas Löschmann; Tina Kop-Weiershausen; Jörg Neudörfl; Frank Rominger

doi:10.1186/1860-5397-2-7

A superior P-H phosphonite: asymmetric allylic substitutions with fenchol-based palladium catalysts

Beilstein J Org Chem. 2006 Mar 30:2:7. doi: 10.1186/1860-5397-2-7.

Authors

Bernd Goldfuss¹, Thomas Löschmann, Tina Kop-Weiershausen, Jörg Neudörfl, Frank Rominger

Affiliation

¹ Institut für Organische Chemie, Universität zu Köln, Germany. goldfuss@uni-koeln.de

Abstract

The fenchol-based P-H phosphonite BIFOP-H exeeds with 65% ee other monodentate ligands in the Pd-catalyzed substitution of 1-phenyl-2-propenyl acetate with dimethylmalonate.