The bacteriologic yield in children with intrathoracic tuberculosis

Clin Infect Dis. 2006 Apr 15;42(8):e69-71. doi: 10.1086/502652. Epub 2006 Mar 6.


This report documents the bacteriologic yield in children who received treatment for intrathoracic tuberculosis in an area where it is highly endemic. A total of 307 children were included in the study, and bacteriologic confirmation was achieved in 122 (62.2%) of 196 children from whom specimens were collected. The lowest bacteriologic yield was recorded for the 69 children with uncomplicated lymph node disease (24 [34.8%] had bacteriologic confirmation). The high overall bacteriologic yield indicates the need to reassess the value of bacteriology-based approaches to diagnosis of intrathoracic tuberculosis in children, particularly in areas of endemicity where they frequently present with advanced disease.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Mycobacterium tuberculosis / isolation & purification*
  • Prospective Studies
  • Respiratory System / microbiology
  • South Africa
  • Tuberculosis, Pulmonary / microbiology*