[Effect of MAGNE-B6 on the clinical and biochemical manifestations of the syndrome of attention deficit and hyperactivity in children]

Eksp Klin Farmakol. Jan-Feb 2006;69(1):74-7.
[Article in Russian]

Abstract

MAGNE-B6 was used for the therapy of a group of 31 children aged from 6 to 12 with attention deficiency and hyperactivity syndrome. The control group included 20 children with similar manifestations of the same pathology, which received a polyvitamin complex. The efficacy of therapy was assessed in the 30th day with the aid of a complex clinical-neuropsychological and biochemical investigations. It was established that the administration of MAGNE-B6 led to improvements in the behavior, decreased the level of anxiety and aggression, improved both large- and small-scale mobility, decreased the level of synkinesis, increased the characteristics of attention, corrected the magnesium homeostasis, and favored normalization of the blood electrolytes. Reliable differences (p < 0.01 or 0.001) between the test and control groups in the degree of expression of the indicated disorders were observed.

Publication types

  • Clinical Trial

MeSH terms

  • Ascorbic Acid / therapeutic use*
  • Attention / drug effects*
  • Attention Deficit Disorder with Hyperactivity / blood
  • Attention Deficit Disorder with Hyperactivity / drug therapy*
  • Attention Deficit Disorder with Hyperactivity / psychology
  • Biological Transport
  • Ca(2+) Mg(2+)-ATPase / metabolism
  • Calcium / blood
  • Child
  • Drug Combinations
  • Erythrocytes / drug effects
  • Erythrocytes / metabolism
  • Female
  • Humans
  • Magnesium / administration & dosage
  • Magnesium / blood
  • Magnesium / therapeutic use*
  • Male
  • Neuropsychological Tests
  • Sodium-Potassium-Exchanging ATPase / metabolism
  • Surveys and Questionnaires
  • Vitamin B 6 / administration & dosage
  • Vitamin B 6 / therapeutic use*

Substances

  • Drug Combinations
  • Magne B6
  • Vitamin B 6
  • Ca(2+) Mg(2+)-ATPase
  • magnesium sodium potassium ATPase
  • Sodium-Potassium-Exchanging ATPase
  • Magnesium
  • Ascorbic Acid
  • Calcium