[Lymphocytes B and NK in Respiratory Allergy]

Rev Alerg Mex. Sep-Oct 2005;52(5):183-7.
[Article in Spanish]

Abstract

Background: High affinity immunoglobulin E (IgE) receptors may activate the mast cell degradation; on the other hand, the ones of low affinity may activate B lymphocytes so they act as antigen-presenting cells and as producers of the same immunoglobulin. As allergic patients produce a great quantity of IgE they are prone to get an infection.

Objective: To quantify the IgE increase in 28 patients with allergic rhinitis or asthma, or both without having received a previous treatment.

Patients and methods: 38 patients with allergic rhinitis, bronchial asthma, allergic conjunctivitis or atopic dermatitis diagnosis were included. B lymphocytes and NK cells immunophenotypification was made. Flow cytometry was used for cells lecture. Data were analyzed with descriptive statistics applying central tendency measurements.

Results: No variations were found in the values of any cell lineage.

Conclusions: Proliferation and activation of B lymphocytes should be considered in allergic diseases as its quantification in serum may be a measurement parameter of allergic activity.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • B-Lymphocytes / immunology*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Killer Cells, Natural / immunology*
  • Male
  • Middle Aged
  • Respiratory Hypersensitivity / blood*
  • Respiratory Hypersensitivity / immunology*