Kimura's disease of the parapharyngeal space

Ear Nose Throat J. 2006 Feb;85(2):106-8.


Kimura's disease is a fairly uncommon inflammatory condition of unknown etiology. It classically presents in young Asian males as tumorlike subcutaneous nodules in the head and neck with associated lymphadenopathy, peripheral eosinophilia, and an elevated serum IgE level. Kimura's disease affects the subcutaneous tissues, salivary glands, and lymph nodes; less common sites in the head and neck include the eyelid and tympanic membrane. We report a case of Kimura's disease of the parapharyngeal space in a 42-year-old Chinese woman. To the best of our knowledge, this is the first report of Kimura's disease at this site.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angiolymphoid Hyperplasia with Eosinophilia / diagnosis*
  • Angiolymphoid Hyperplasia with Eosinophilia / pathology
  • Angiolymphoid Hyperplasia with Eosinophilia / therapy*
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use
  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / therapeutic use
  • Biopsy, Needle
  • Diagnosis, Differential
  • Drug Therapy, Combination
  • Female
  • Follow-Up Studies
  • Humans
  • Hydroxyurea / administration & dosage
  • Hydroxyurea / therapeutic use
  • Pharyngeal Diseases / diagnosis*
  • Pharyngeal Diseases / pathology
  • Pharyngeal Diseases / therapy*
  • Prednisolone / administration & dosage
  • Prednisolone / therapeutic use
  • Radiotherapy, Adjuvant
  • Tomography, X-Ray Computed
  • Treatment Outcome


  • Anti-Inflammatory Agents
  • Antineoplastic Agents
  • Prednisolone
  • Hydroxyurea