The immunological synapse: kinases in T cell signalling as potential drug targets

Immunol Lett. 2006 May 15;105(1):3-5. doi: 10.1016/j.imlet.2005.12.003.

Abstract

This international workshop on key signalling molecules in lymphocyte activation and immune regulation was held in Grossziethen, Germany from November 02-04, 2005 and brought together molecular, cellular, and clinical immunologists whose common goal is to develop ways of manipulating the immune response in order to avert T cell effector functions that are of significant relevance for pathogenesis in different diseases, including dermatological (psoriasis, atopic dermatitis and allergic contact allergy) and other indications (e.g. asthma, rheumatoid arthritis, multiple sclerosis and transplant rejection).

Publication types

  • Congress

MeSH terms

  • Animals
  • Humans
  • Lymphocyte Activation
  • Mice
  • Models, Immunological
  • Protein Kinases / immunology*
  • Signal Transduction
  • T-Lymphocytes / drug effects
  • T-Lymphocytes / enzymology*
  • T-Lymphocytes / immunology*

Substances

  • Protein Kinases