Gene expression profiling as novel tool in experimental asthma research

A M Dittrich; D Quarcoo; M Krokowski; B Ahrens; E Hamelmann

doi:10.1016/j.etp.2006.02.003

Gene expression profiling as novel tool in experimental asthma research

Exp Toxicol Pathol. 2006 Jun:57 Suppl 2:31-3. doi: 10.1016/j.etp.2006.02.003. Epub 2006 Mar 31.

Authors

A M Dittrich¹, D Quarcoo, M Krokowski, B Ahrens, E Hamelmann

Affiliation

¹ Department of Pediatric Pneumonology and Immunology, Charité Universitätsmedizin, Augustenburger Platz 1, 13353 Berlin, Germany.

PMID: 16580825
DOI: 10.1016/j.etp.2006.02.003

Abstract

With the advances achieved in decoding of the genetic structures of species and the novel possibilities of simultaneous measurements of the regulation of all genes of a given tissue, the last 10 years have seen a massive increase of our knowledge about genetic regulation of diseases. Additionally, the possibilities to control transcriptional processes within the cells will speed up the process of disentangling the various pathways leading to disease.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Asthma / genetics*
Asthma / immunology
Asthma / pathology
Bronchial Hyperreactivity / genetics*
Bronchial Hyperreactivity / immunology
Bronchial Hyperreactivity / pathology
Disease Models, Animal*
Gene Expression Profiling*
Gene Expression Regulation
Genetic Predisposition to Disease
Humans
Mice
Transcription, Genetic