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. 2006 Jun 15;16(12):3255-7.
doi: 10.1016/j.bmcl.2006.03.027. Epub 2006 Apr 11.

Two Novel Furan Derivatives From Phellinus Linteus With Anti-Complement Activity

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Two Novel Furan Derivatives From Phellinus Linteus With Anti-Complement Activity

Byung-Sun Min et al. Bioorg Med Chem Lett. .

Abstract

Two novel stereoisomers of furan derivatives, phellinusfurans A (1) and B (2), were isolated from the fruiting body of Phellinus linteus. Their structures were elucidated by spectroscopic analysis. Compounds 1 and 2 exhibited significant anti-complement activity with IC50 values of 33.6 and 33.7 microM, respectively, in inhibiting the hemolytic activity of human serum against erythrocytes.

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