Cost-effectiveness of preventing depression in primary care patients: randomised trial

Br J Psychiatry. 2006 Apr:188:330-6. doi: 10.1192/bjp.188.4.330.

Abstract

Background: Little is known about the cost-effectiveness of preventing mental disorders.

Aims: To study the cost-effectiveness of care as usual plus minimal contact psychotherapy relative to usual care alone in preventing depressive disorder.

Method: An economic evaluation was conducted alongside a randomised clinical trial. Primary care patients with sub-threshold depression were assigned to minimal contact psychotherapy plus usual care (n=107) or to usual care alone (n=109).

Results: Primary care patients with sub-threshold depression benefited from minimal contact psychotherapy as it reduced the risk of developing a full-blown depressive disorder from 18% to 12%. In addition, this intervention had a 70% probability of being more cost-effective than usual care alone. A sensitivity analysis indicated the robustness of these results.

Conclusions: Over 1 year adjunctive minimal contact psychotherapy improved outcomes and generated lower costs. This intervention is therefore superior to usual care alone in terms of cost-effectiveness.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cognitive Behavioral Therapy / economics*
  • Cost-Benefit Analysis
  • Depressive Disorder / economics
  • Depressive Disorder / prevention & control*
  • Female
  • Health Care Costs
  • Humans
  • Male
  • Middle Aged
  • Primary Health Care / economics