[Palliative radiotherapy for metastatic bone tumor]

Clin Calcium. 2006 Apr;16(4):641- 45.
[Article in Japanese]


Bone metastases are one of the most common conditions requiring radiation therapy today. Its main aim is relief of bone pain, prevention of pathological bone fractures as well as its healing, with anticipated effect upon improving mobility, function, and quality of life. For localized bone pain, external beam radiation therapy (EBRT) will be successful in reducing pain in some 80% of patients. However, optimal fraction dose and total doses of EBRT required for pain relief have been unknown. According to the recent reports, carbon ion radiotherapy seems to be a safe and effective modality in the management of metastatic bone tumor not eligible for conventional EBRT. For scattered painful metastases, the systemic administration of radioisotopes is thought to be effective.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Bone Neoplasms / complications
  • Bone Neoplasms / radiotherapy*
  • Bone Neoplasms / secondary*
  • Brachytherapy
  • Carbon Radioisotopes / therapeutic use
  • Combined Modality Therapy
  • Dose Fractionation, Radiation
  • Humans
  • Iodine Radioisotopes / therapeutic use
  • Pain / etiology
  • Pain / radiotherapy*
  • Palliative Care / methods*
  • Radiotherapy Dosage
  • Radiotherapy, High-Energy
  • Strontium Radioisotopes / therapeutic use


  • Anti-Inflammatory Agents, Non-Steroidal
  • Carbon Radioisotopes
  • Iodine Radioisotopes
  • Strontium Radioisotopes