Two putative c-type multiheme cytochromes required for the expression of OmcB, an outer membrane protein essential for optimal Fe(III) reduction in Geobacter sulfurreducens

J Bacteriol. 2006 Apr;188(8):3138-42. doi: 10.1128/JB.188.8.3138-3142.2006.


Deletion of two homologous Geobacter sulfurreducens c-type cytochrome genes, omcG and omcH, decreased the rate of Fe(III) reduction and decreased the level of an outer membrane cytochrome critical for Fe(III) reduction, OmcB, without affecting its transcription. Expression of either gene restored Fe(III) reduction and OmcB expression, suggesting functional similarity.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Bacterial Outer Membrane Proteins / biosynthesis*
  • Bacterial Proteins / biosynthesis
  • Blotting, Northern
  • Blotting, Western
  • Cytochromes c / genetics
  • Cytochromes c / metabolism*
  • Ferric Compounds / metabolism*
  • Gene Deletion
  • Gene Expression
  • Genes, Bacterial
  • Geobacter / genetics
  • Geobacter / metabolism*
  • Oxidation-Reduction
  • RNA, Bacterial / analysis
  • RNA, Messenger / analysis


  • Bacterial Outer Membrane Proteins
  • Bacterial Proteins
  • Ferric Compounds
  • OmcB protein, bacteria
  • RNA, Bacterial
  • RNA, Messenger
  • Cytochromes c