Digoxin and mexiletine sensitivity in a Collie with the MDR1 mutation

J Vet Intern Med. Mar-Apr 2006;20(2):415-7. doi: 10.1892/0891-6640(2006)20[415:damsia]2.0.co;2.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / genetics*
  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / metabolism*
  • Animals
  • Anti-Arrhythmia Agents / adverse effects
  • Cardiotonic Agents / adverse effects
  • Central Nervous System Diseases / chemically induced
  • Central Nervous System Diseases / genetics
  • Central Nervous System Diseases / veterinary
  • Digoxin / adverse effects*
  • Dog Diseases / chemically induced*
  • Dog Diseases / genetics*
  • Dogs
  • Female
  • Mexiletine / adverse effects*
  • Mutation / genetics

Substances

  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • Anti-Arrhythmia Agents
  • Cardiotonic Agents
  • Mexiletine
  • Digoxin