Stereoselective synthesis of protected 1,2-diols and 1,2,3-triols by a tandem hydroboration-coupling sequence

Org Lett. 2006 Apr 13;8(8):1629-32. doi: 10.1021/ol0602194.

Abstract

[reaction: see text] A new approach to complex chiral diols and polyols is described utilizing a tandem hydroboration/Suzuki cross-coupling reaction. This method utilizes the versatility of a glycolate-derived chiral template.