Identification of truncated RUNX1 and RUNX1-PRDM16 fusion transcripts in a case of t(1;21)(p36;q22)-positive therapy-related AML

Leukemia. 2006 Jun;20(6):1187-9. doi: 10.1038/sj.leu.2404210.
No abstract available

Publication types

  • Case Reports
  • Comparative Study
  • Letter

MeSH terms

  • Acute Disease
  • Chromosomes, Human, Pair 1*
  • Chromosomes, Human, Pair 21*
  • Core Binding Factor Alpha 2 Subunit / genetics*
  • DNA-Binding Proteins / genetics*
  • Fatal Outcome
  • Female
  • Humans
  • Leukemia, Myeloid / diagnosis
  • Leukemia, Myeloid / genetics*
  • Leukemia, Myeloid / therapy
  • Middle Aged
  • Oncogene Proteins, Fusion / genetics*
  • Reverse Transcriptase Polymerase Chain Reaction
  • Transcription Factors / genetics*
  • Transcription, Genetic*
  • Translocation, Genetic

Substances

  • Core Binding Factor Alpha 2 Subunit
  • DNA-Binding Proteins
  • Oncogene Proteins, Fusion
  • PRDM16 protein, human
  • RUNX1 protein, human
  • Transcription Factors