A case of acute heart failure associated with Guillain-Barré syndrome

Neurol Sci. 2006 Feb;26(6):447-50. doi: 10.1007/s10072-006-0531-0.


Guillain-Barré syndrome (GBS) is a disease of the peripheral nervous system, which is caused by aberrant immune responses directed against some components of peripheral nerves. GBS is rarely accompanied by cardiovascular involvement. We describe a case of acute neuropathy complicated by sudden heart failure and left ventricular dysfunction which had a presumably neurogenic origin. Pathogenesis of acute heart failure is probably due to transitorial stunned myocardium and neurogenic cardiac injury. We show a rare case of transitorial and acute cardiac dysfunction by echocardiography and laboratory markers of heart failure.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Electrocardiography / methods
  • Guillain-Barre Syndrome / complications*
  • Guillain-Barre Syndrome / metabolism
  • Guillain-Barre Syndrome / pathology
  • Heart Failure / complications*
  • Heart Failure / metabolism
  • Heart Failure / pathology
  • Humans
  • Male
  • Natriuretic Peptide, Brain / metabolism
  • Ventricular Dysfunction, Left / complications*
  • Ventricular Dysfunction, Left / metabolism
  • Ventricular Dysfunction, Left / pathology


  • Natriuretic Peptide, Brain