Standing waves in the FitzHugh-Nagumo model of cardiac electrical activity

Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Feb;73(2 Pt 1):021908. doi: 10.1103/PhysRevE.73.021908. Epub 2006 Feb 16.

Abstract

When excitable media are submitted to appropriate time dependent boundary conditions, a standing wavelike pattern can be observed in the system, as shown in recent experiments. In the present analysis, the physical mechanism explaining the occurrence of such space-time patterns is shown to be a competition between Ohmic diffusion and an action potential propagation across the system, coupled with the existence of refractory states for excitable media.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Action Potentials / physiology*
  • Animals
  • Biological Clocks / physiology*
  • Computer Simulation
  • Heart Conduction System / physiology*
  • Humans
  • Models, Cardiovascular*
  • Myocytes, Cardiac / physiology*
  • Synaptic Transmission / physiology*