Antibiotic susceptibility patterns of Neisseria gonorrhoeae isolates in Port Elizabeth

S Afr Med J. 2006 Mar;96(3):225-6.

Abstract

Objective: To survey the antibiotic susceptibility of Neisseria gonorrhoeae isolates.

Design: This was a cohort analytical study.

Setting: Three clinics serving different areas in Port Elizabeth. Outcome measures. Prevalence of antibiotic-resistant N. gonorrhoeae isolates.

Results: Twenty-one of the 35 isolates (60%) were resistant to ciprofloxacin, while 28 (80%) showed resistance to erythromycin, 17 (48.6%) to penicillin, 3 (8.6%) to doxycycline, 11 (31.4%) to spectinomycin and 33 (94.3%) to tetracycline.

Conclusion: To ensure effective treatment of gonorrhoea, continued surveillance of antimicrobial susceptibility is necessary.

MeSH terms

  • Adolescent
  • Adult
  • Anti-Infective Agents / pharmacology*
  • Ciprofloxacin / pharmacology
  • Cohort Studies
  • Doxycycline / pharmacology
  • Drug Resistance, Bacterial*
  • Erythromycin / pharmacology
  • Female
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Neisseria gonorrhoeae / drug effects*
  • Penicillins / pharmacology
  • South Africa
  • Spectinomycin / pharmacology
  • Tetracycline / pharmacology

Substances

  • Anti-Infective Agents
  • Penicillins
  • Ciprofloxacin
  • Erythromycin
  • Spectinomycin
  • Tetracycline
  • Doxycycline