Side effects of antidepressants: an overview

Cleve Clin J Med. 2006 Apr;73(4):351-3, 356-61. doi: 10.3949/ccjm.73.4.351.


Adverse effects of antidepressant drugs can decrease compliance and delay recovery. It is therefore crucial to consider potential side effects when choosing an antidepressant. Although there is no perfect antidepressant that works quickly and is completely free of adverse reactions, newer antidepressants are safer, better tolerated, and associated with a lower rate of noncompliance.

Publication types

  • Review

MeSH terms

  • Antidepressive Agents / adverse effects*
  • Antidepressive Agents / pharmacokinetics
  • Humans


  • Antidepressive Agents